Molecular chaperone

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&nbsp;Molecular chaperones are proteins which its function is to help [https://teaching.ncl.ac.uk/bms/wiki/index.php/Protein protein]s in their folding process. It helps in folding the newly synthesised protein into correct orientation for their specific functions.<ref>https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/chaperone-protein</ref><ref>https://www.nature.com/articles/nature10317</ref>  
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Molecular [[chaperones|chaperones]] are proteins which its function is to help [[proteins|proteins]] in their folding process. It helps in folding the newly synthesised protein into correct orientation for their specific functions<ref>https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/chaperone-protein</ref><ref>https://www.nature.com/articles/nature10317</ref>.
  
 
There are three types of chaperones&nbsp;:  
 
There are three types of chaperones&nbsp;:  
  
#Folding chaperones&nbsp;: helps in folding of newly synthesised proteins.  
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#Folding chaperones: helps in the folding of newly synthesised proteins.  
#Holding chaperones&nbsp;: binds to misfolded proteins and transfer them to folding chaperones.  
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#Holding chaperones: binds to misfolded proteins and transfer them to folding chaperones.  
#Unfolding chaperones&nbsp;: unfold misfolded proteins for degradation using [https://teaching.ncl.ac.uk/bms/wiki/index.php/Proteasome proteasome] unit during proteostasis.<ref>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340576/</ref>
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#Unfolding chaperones: unfold misfolded proteins for degradation using [[proteasome|proteasome]] unit during proteostasis<ref>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340576/</ref>.
  
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=== References ===
 
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<u>'''References:'''</u>
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Latest revision as of 07:54, 23 November 2018

Molecular chaperones are proteins which its function is to help proteins in their folding process. It helps in folding the newly synthesised protein into correct orientation for their specific functions[1][2].

There are three types of chaperones :

  1. Folding chaperones: helps in the folding of newly synthesised proteins.
  2. Holding chaperones: binds to misfolded proteins and transfer them to folding chaperones.
  3. Unfolding chaperones: unfold misfolded proteins for degradation using proteasome unit during proteostasis[3].

References

  1. https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/chaperone-protein
  2. https://www.nature.com/articles/nature10317
  3. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340576/
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