Molecular chaperone

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Molecular chaperones are proteins which its function is to help proteins in their folding process. It helps in folding the newly synthesised protein into correct orientation for their specific functions[1][2].

There are three types of chaperones :

  1. Folding chaperones: helps in the folding of newly synthesised proteins.
  2. Holding chaperones: binds to misfolded proteins and transfer them to folding chaperones.
  3. Unfolding chaperones: unfold misfolded proteins for degradation using proteasome unit during proteostasis[3].

References

  1. https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/chaperone-protein
  2. https://www.nature.com/articles/nature10317
  3. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340576/
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