Morpholino

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'''Description:'''
+
== '''Description:''' ==
  
 
* Small oligomer of synthetic nucleotide analogues that block gene expression  
 
* Small oligomer of synthetic nucleotide analogues that block gene expression  
 
*25bp length
 
*25bp length
  
'''Function:'''
+
== '''Function:''' ==
  
 
*attaches to mRNA, pre/mature, to cause gene knockdown  
 
*attaches to mRNA, pre/mature, to cause gene knockdown  
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*sits on splice site, an intron-exon junction, making a double stranded RNA, blocking spliceosome which will create truncated/no protein<br>
 
*sits on splice site, an intron-exon junction, making a double stranded RNA, blocking spliceosome which will create truncated/no protein<br>
  
<br>
 
  
----
 
  
'''References
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== '''References'''  ==
  
<references />&nbsp;
+
== <references />&nbsp; ==
  
 
Shukla, Arun K., editor. “The Zebrafish: Disease Models and Chemical Screens.” Methods in Cell Biology, vol. 105, no. 12, 2011, pp. 273–308., doi:10.1016/c2009-0-62387-4.<br>  
 
Shukla, Arun K., editor. “The Zebrafish: Disease Models and Chemical Screens.” Methods in Cell Biology, vol. 105, no. 12, 2011, pp. 273–308., doi:10.1016/c2009-0-62387-4.<br>  
  
<references />
+
<br>

Revision as of 12:29, 16 November 2017

Contents

Description:

Function:

On mature mRNA:

On pre-mRNA:


References

 

Shukla, Arun K., editor. “The Zebrafish: Disease Models and Chemical Screens.” Methods in Cell Biology, vol. 105, no. 12, 2011, pp. 273–308., doi:10.1016/c2009-0-62387-4.


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