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The myofibril is a long contractile unit made of the myofilaments actin and myosin which form the sarcomere. They line up parallel to one another forming cylindrical structures which bundle together into a muscle fibre. The regular arrangement of cross striations of sarcomeres, which can be observed under a low magnification electron microscope, attribute to the alternative name given to skeletal muscles: striated muscle. An electron micrograph of myofibrils shows differently shaded bands. These are representative of the different density protein filaments:


  1. Alberts B, Johnson A, Lewis J, Raff M, Roberts K and Walter P. (2008) Molecular Biology of The Cell, 5th edition, New York: Garland Science
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