Nonsense mutation

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Nonsense mutation is when there is a nucleotide substitution causing a different amino acid to be coded for, which creates a stop codon . This causes the protein that is being encoded for to be truncated due to the premature termination of translation[1].

References

[1] Hartl, D. and Jones, E. (2009) Genetics: Genes and Genomes, U.S.A: Jones and Bartlett, page 515

 

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