O-glycosidic bond

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The bond between a sugar and another molecule, usually another sugar, to create oligosaccharides. The chemical bond is formed by a condensation reaction, the hydroxyl group on the sugar reacts with the other molecule forming a glycosidic bond and releasing a molecule of water. For example, the disaccharide maltose consists of two D-glucose residues which are joined by a glycosidic bond between the alpha-anomeric form of C1 on one of the glucose molecules and the hydroxyl oxygen atom on C4 of the adjacent glucose molecule [1].


  1. Berg, J, Tymoczko, J and Stryer, L (2012). Biochemistry. 7th ed. Basinstoke: W. H Freeman and Company. p337.
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