Okasaki fragments

From The School of Biomedical Sciences Wiki
Revision as of 15:03, 1 December 2015 by 140660041 (Talk | contribs)
Jump to: navigation, search

Okasaki fragments are short fragments of DNA formed on the lagging strand during bidirectional semiconservative DNA replication. The strands are later fused together by DNA ligase to form the full, unfragmented DNA strand.[1] Each new origin of replication (where the DNA polymerase joins) requires a separate RNA primer. 

References:

  1. Sakabe K, Okazaki R (December 1966). "A unique property of the replicating region of chromosomal DNA". Biochimica et Biophysica Acta 129 (3): 651–54. doi:10.1016/0005-2787(66)90088-8. PMID 5337977.
Personal tools
Namespaces
Variants
Actions
Navigation
Toolbox