Open state probability

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 Open state probability, also written as O.S.P or Po , is a measure of the proportion of the total recording time that an ion channel spends in its open state. 


O.S.P = Open state time / Total recording time

(which can be written as a percentage when the answer is multiplied by 100)



The Po value is useful when counting the number of ion channels (N) in a cell because we are able to substitute its value (along with the rest of the values) into the following equation:

Itotal  =  N  x  Po  x  i

Itotal =  Whole cell current

N = Number of active channels

Po = Open state probability

i = Single channel current


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