PI3K RBD ( Phosoinositide 3-kinase Ras Binding domain), is a domain found in PI3K molecules that binds to the Ras protein which is key to intracellular signalling. Activated Ras will bind to p110 subunit activating PI3K alpha. To a lesser extent Ras will also activate PY3K gamma.
1.RAS binding domain(Author unknown) http://www.mrc-lmb.cam.ac.uk/rlw/text/pi3k%20web%20pages/rbd.html. Accessed 24/10/2012.