Phosphofructokinase

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(Created page with " Phosphofructokinase (PFK) is a fundamental enzyme in the glycolitic pathway. As the name suggests, the enzyme acts on the intermediate compound 'phosphofructose'; its prope...")
 
(Good edit. However, zero links (so I added some), and the page could do with some references.)
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 Phosphofructokinase (PFK) is a fundamental enzyme in the glycolitic pathway. As the name suggests, the enzyme acts on the intermediate compound 'phosphofructose'; its proper name being fructose-6-phosphate. The suffix 'kinase' indicates its function as a phosphorylator. The product of this enzyme-subtrate interaction is fructose 1,6 bisphosphate, which subsequently is hydrolysed to glyceralaldehyde 3 phosphate and dihydroxyacetone phosphate. 
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Phosphofructokinase (PFK) is a fundamental [[enzyme|enzyme]] in the [[glycolitic pathway|glycolitic pathway]]. As the name suggests, the enzyme acts on the intermediate compound 'phosphofructose'; its proper name being [[fructose-6-phosphate|fructose-6-phosphate]]. The suffix '[[kinase|kinase]]' indicates its function as a phosphorylator. The product of this enzyme-subtrate interaction is [[Fructose-1,6-bisphosphate|fructose 1,6 bisphosphate]], which subsequently is [[hydrolysed|hydrolysed]] to [[glyceralaldehyde 3 phosphate|glyceralaldehyde 3 phosphate]] and [[dihydroxyacetone phosphate|dihydroxyacetone phosphate]].   
  
PFK is an allosteric enzyme; meaning that its action is regulated by activator and inhibitor effector molecules; in this case AMP and ATP respectively. 
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PFK is an [[allosteric enzyme|allosteric enzyme]]; meaning that its action is regulated by activator and inhibitor effector molecules; in this case [[AMP|AMP]] and [[ATP|ATP]] respectively.   
  
Phosphofructokinase has antagonistic action with the enzyme Fructose 1,6-bisphosphatase; a dephosphorylator. 
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Phosphofructokinase has antagonistic action with the enzyme [[Fructose 1,6-bisphosphatase|Fructose 1,6-bisphosphatase]]; a dephosphorylator. 

Revision as of 14:06, 3 December 2016

Phosphofructokinase (PFK) is a fundamental enzyme in the glycolitic pathway. As the name suggests, the enzyme acts on the intermediate compound 'phosphofructose'; its proper name being fructose-6-phosphate. The suffix 'kinase' indicates its function as a phosphorylator. The product of this enzyme-subtrate interaction is fructose 1,6 bisphosphate, which subsequently is hydrolysed to glyceralaldehyde 3 phosphate and dihydroxyacetone phosphate

PFK is an allosteric enzyme; meaning that its action is regulated by activator and inhibitor effector molecules; in this case AMP and ATP respectively. 

Phosphofructokinase has antagonistic action with the enzyme Fructose 1,6-bisphosphatase; a dephosphorylator. 

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