Pre Initiation Complex

From The School of Biomedical Sciences Wiki
(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
 
== Pre Initiation Complex (PIC)<br>  ==
 
== Pre Initiation Complex (PIC)<br>  ==
  
In eukaryotic gene expression the Pre Initiation Complex (PIC) mediates the binding between the genome's promoter and RNA&nbsp;polymerase. Each type of RNA&nbsp;polymerase has a different PIC<br>  
+
In [[Eukaryotes|eukaryotic]] [[gene ]]expression the Pre Initiation Complex (PIC) mediates the binding between the [[Genome|genome]]'s [[Promoter|promoter ]]and [[RNA_polymerase|RNA&nbsp;polymerase]]. Each type of RNA&nbsp;polymerase has a different PIC<br>  
  
 
== Subunits<br>  ==
 
== Subunits<br>  ==
Line 7: Line 7:
 
The complexicity of PIC&nbsp;varies between the types of eukaryotic RNA polymerase. For polymerases I&nbsp;and III the complex consists of only a few subunits.<br>  
 
The complexicity of PIC&nbsp;varies between the types of eukaryotic RNA polymerase. For polymerases I&nbsp;and III the complex consists of only a few subunits.<br>  
  
For polymerase II the PIC&nbsp;is far more complex. It consists of 6 General Transcription Factors (GTF). TFIID is the core recognition protein and binds to the [[Tata box|TATA&nbsp;box]]<br>  
+
For polymerase II the PIC&nbsp;is far more complex. It consists of 6 General Transcription Factors (GTF). TFIID is the core recognition [[Protein|protein ]]and binds to the [[Tata box|TATA&nbsp;box]]. <br>  
  
 
<br>
 
<br>

Revision as of 18:53, 20 November 2011

Pre Initiation Complex (PIC)

In eukaryotic gene expression the Pre Initiation Complex (PIC) mediates the binding between the genome's promoter and RNA polymerase. Each type of RNA polymerase has a different PIC

Subunits

The complexicity of PIC varies between the types of eukaryotic RNA polymerase. For polymerases I and III the complex consists of only a few subunits.

For polymerase II the PIC is far more complex. It consists of 6 General Transcription Factors (GTF). TFIID is the core recognition protein and binds to the TATA box.


Personal tools
Namespaces
Variants
Actions
Navigation
Toolbox