Primary structure

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The primary structure is the first structure of a [[Protein|protein]] made. It is the underlying basis of how the [[Proteins|protein]] folds up and what&nbsp;conformational shape&nbsp;it takes. It is made of a linear string of [[Amino acid|amino acids]]&nbsp;([[Polypeptide|polypeptide]] chain)&nbsp;which have been coded for by [[Codon|codons]] by [[DNA|DNA]] base sequences in the translation process. Peptide bonds form between amino acids to attach them together. Each [[Amino acid|amino acid]] is individually different and the&nbsp;different&nbsp;chemistries of the side chains allow the [[Polypeptide|polypeptide chain]] to fold up in&nbsp;a unique way allowing&nbsp;a specific function&nbsp;for that [[Protein|protein]]&nbsp;<ref>Molecular Biology of the Cell, 5th edition, Bruce Alberts et al, p127, p131.</ref>.  
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The primary structure is the first structure of a [[Protein|protein]] made. It is the underlying basis of how the [[Proteins|protein]] folds up and what&nbsp;conformational shape&nbsp;it takes. It is made of a linear string of [[Amino acid|amino acids]]&nbsp;([[Polypeptide|polypeptide]] chain)&nbsp;which have been coded for by [[Codon|codons]] by [[DNA|DNA]] base sequences in the translation process. Peptide bonds form between amino acids to attach them together<sup>[2]</sup>. Each [[Amino acid|amino acid]] is individually different and the&nbsp;different&nbsp;chemistries of the side chains allow the [[Polypeptide|polypeptide chain]] to fold up in&nbsp;a unique way allowing&nbsp;a specific function&nbsp;for that [[Protein|protein]]&nbsp;<ref>Molecular Biology of the Cell, 5th edition, Bruce Alberts et al, p127, p131.</ref>.  
  
 
=== References  ===
 
=== References  ===

Revision as of 11:43, 2 December 2015

The primary structure is the first structure of a protein made. It is the underlying basis of how the protein folds up and what conformational shape it takes. It is made of a linear string of amino acids (polypeptide chain) which have been coded for by codons by DNA base sequences in the translation process. Peptide bonds form between amino acids to attach them together[2]. Each amino acid is individually different and the different chemistries of the side chains allow the polypeptide chain to fold up in a unique way allowing a specific function for that protein [1].

References

  1. Molecular Biology of the Cell, 5th edition, Bruce Alberts et al, p127, p131.

2. Burrows C, Elder E, Hayden C, McCurrie R, Rogers R, Thompson H, Towle J, Tyler M (eds) 2012, AS-Level Biology, the complete course for OCR, Coordination Group Publications, Newcastle Upon Tyne p.108

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