Protein Kinase A

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[[Protein kinases|Protein kinases]] are [[Enzymes|enzymes]] which catalyse the [[Phosphorylation|phosphorylation]] of [[Proteins|proteins]]. [[ATP|ATP]] often supplies the phosphate for the reaction. Protein kinases have differing levels of specificity.  Some will only phosphorylate one particular protein but others, such as protein kinase A, can phosphorylate many different proteins. Protein kinase A is involved in the ‘fight or flight’ response in mammals. In this response, the hormone adrenaline causes the production of [[CAMP|cAMP]], a [[Secondary messenger|secondary messenger]]. cAMP then activates protein kinase A. Protein kinase A then activates [[Phosphorylase kinase|phosphorylase kinase]] which continues the pathway for the breakdown of [[Glycogen|glycogen]]. This pathway occurs in the [[Muscle|muscle]] and in the [[Liver|liver]] but the [[Hormone|hormone]] is [[Glucagon|glucagon]] in the liver.
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See [[Protein kinase A|Protein kinase A]]
 
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[[Image:Protein Kinase A.png]]<ref>Linder T, Melby AE. Cyclic AMP. Available at: http://courses.washington.edu/conj/gprotein/cyclicamp.htm</ref>
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=== References  ===
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<references />
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Latest revision as of 08:07, 29 November 2016

See Protein kinase A

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