Proteomics

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Proteomics is the study of&nbsp; total proteins which is expressed by a cell, tissue&nbsp;or an organism<ref name="null">Trent, R.J. (2012) Molecular Medicine Genomics to personalized healthcare : Proteomics. 4 , 137. USA : Elsevier.</ref>. Meanwhile, genomics is the study of structure and roles of the whole gene products<ref name="null">Primrose S.B. , Twyman R.M. (2003). Principle of Genome Analysis and Genomics. 3, 9. Hong Kong: Graphicraft Limited.</ref>. There are a few&nbsp;crucial&nbsp;differences between proteomics and genomics. In biological fluids such as plasma, serum, urine, cells and tissues, a marker called as "Proteomic biomarkers" is used to mark the molecules<ref>Primrose S.B. , Twyman R.M. (2003). Principle of Genome Analysis and Genomics. 3, 9. Hong Kong: Graphicraft Limited.</ref>. Besides, if there is a stimuli from the environment or surroundings, the proteome(proteins) will react with the stimuli and keep changing in constant<ref>Primrose S.B. , Twyman R.M. (2003). Principle of Genome Analysis and Genomics. 3, 9. Hong Kong: Graphicraft Limited.</ref>. Furthermore,&nbsp;in every cells or tissues, the proteome is different from each other due to different genes carried<ref>Primrose S.B. , Twyman R.M. (2003). Principle of Genome Analysis and Genomics. 3, 9. Hong Kong: Graphicraft Limited.</ref>. Existence of&nbsp; post-translational modifications and protein conformation will cause in addition of the complexity<ref>Primrose S.B. , Twyman R.M. (2003). Principle of Genome Analysis and Genomics. 3, 9. Hong Kong: Graphicraft Limited.</ref>. Thus, only Polymerase Chain Reaction(PCR)&nbsp; produces total of proteome faster and ease to amplify them to an assay<ref>Primrose S.B. , Twyman R.M. (2003). Principle of Genome Analysis and Genomics. 3, 9. Hong Kong: Graphicraft Limited.</ref>. These reasons proves that the proteome potrays the transcriptome more than the genome itself<ref>Primrose S.B. , Twyman R.M. (2003). Principle of Genome Analysis and Genomics. 3, 9. Hong Kong: Graphicraft Limited.</ref>.
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Proteomics is the study of&nbsp; total proteins which is expressed by a cell, tissue&nbsp;or an organism<ref name="null">Trent, R.J. (2012) Molecular Medicine Genomics to personalized healthcare: Proteomics. 4 , 137. USA :Elsevier.</ref>. Meanwhile, genomics is the study of structure and roles of the whole gene products<ref name="null">Primrose S.B. , Twyman R.M. (2003). Principle of Genome Analysis and Genomics. 3, 9. Hong Kong: Graphicraft Limited.</ref>. There are a few&nbsp;crucial&nbsp;differences between proteomics and genomics. In biological fluids such as plasma, serum, urine, cells and tissues, a marker called as "Proteomic biomarkers" is used to mark the molecules<ref>Primrose S.B. , Twyman R.M. (2003). Principle of Genome Analysis and Genomics. 3, 9. Hong Kong: Graphicraft Limited.</ref>. Besides, if there is a stimuli from the environment or surroundings, the proteome(proteins) will react with the stimuli and keep changing in constant<ref>Primrose S.B. , Twyman R.M. (2003). Principle of Genome Analysis and Genomics. 3, 9. Hong Kong: Graphicraft Limited.</ref>. Furthermore,&nbsp;in every cells or tissues, the proteome is different from each other due to different genes carried<ref>Primrose S.B. , Twyman R.M. (2003). Principle of Genome Analysis and Genomics. 3, 9. Hong Kong: Graphicraft Limited.</ref>. Existence of&nbsp; post-translational modifications and protein conformation will cause in addition of the complexity<ref>Primrose S.B. , Twyman R.M. (2003). Principle of Genome Analysis and Genomics. 3, 9. Hong Kong: Graphicraft Limited.</ref>. Thus, only Polymerase Chain Reaction(PCR)&nbsp; produces total of proteome faster and ease to amplify them to an assay<ref>Primrose S.B. , Twyman R.M. (2003). Principle of Genome Analysis and Genomics. 3, 9. Hong Kong: Graphicraft Limited.</ref>. These reasons proves that the proteome potrays the transcriptome more than the genome itself<ref>Primrose S.B. , Twyman R.M. (2003). Principle of Genome Analysis and Genomics. 3, 9. Hong Kong: Graphicraft Limited.</ref>.

Revision as of 02:02, 22 October 2015

Proteomics is the study of  total proteins which is expressed by a cell, tissue or an organism[1]. Meanwhile, genomics is the study of structure and roles of the whole gene products[1]. There are a few crucial differences between proteomics and genomics. In biological fluids such as plasma, serum, urine, cells and tissues, a marker called as "Proteomic biomarkers" is used to mark the molecules[2]. Besides, if there is a stimuli from the environment or surroundings, the proteome(proteins) will react with the stimuli and keep changing in constant[3]. Furthermore, in every cells or tissues, the proteome is different from each other due to different genes carried[4]. Existence of  post-translational modifications and protein conformation will cause in addition of the complexity[5]. Thus, only Polymerase Chain Reaction(PCR)  produces total of proteome faster and ease to amplify them to an assay[6]. These reasons proves that the proteome potrays the transcriptome more than the genome itself[7].


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