Proteomics is the study of total proteins which is expressed by a cell, tissue or an organism. Meanwhile, genomics is the study of structure and roles of the whole gene products. There are a few crucial differences between proteomics and genomics. In biological fluids such as plasma, serum, urine, cells and tissues, a marker called as "Proteomic biomarkers" is used to mark the molecules. Besides, if there is a stimuli from the environment or surroundings, the proteome(proteins) will react with the stimuli and keep changing in constant. Furthermore, in every cells or tissues, the proteome is different from each other due to different genes carried. Existence of post-translational modifications and protein conformation will cause in addition of the complexity. Thus, only Polymerase Chain Reaction(PCR) produces total of proteome faster and ease to amplify them to an assay. These reasons proves that the proteome potrays the transcriptome more than the genome itself.
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