Proteomics

From The School of Biomedical Sciences Wiki
Revision as of 03:24, 22 October 2015 by 150015802 (Talk | contribs)
Jump to: navigation, search

Proteomics is the study of  total proteins which is expressed by a cell, tissue or an organism[1]. Meanwhile, genomics is the study of structure and roles of the whole gene products[2]. There are a few crucial differences between proteomics and genomics. In biological fluids such as plasma, serum, urine, cells and tissues, a marker called as "Proteomic biomarkers" is used to mark the molecules[3]. Besides, if there is a stimuli from the environment or surroundings, the proteome(proteins) will react with the stimuli and keep changing in constant[4]. Furthermore, in every cells or tissues, the proteome is different from each other due to different genes carried[5]. Existence of  post-translational modifications and protein conformation will cause in addition of the complexity[6]. Thus, only Polymerase Chain Reaction(PCR)  produces total of proteome faster and ease to amplify them to an assay[7]. These reasons proves that the proteome potrays the transcriptome more than the genome itself[8].


Reference

  1. Trent, R.J. (2012) Molecular Medicine Genomics to personalized healthcare: Proteomics, 4th Edition, USA :Elsevier. Chapter 4, Page 137
  2. Primrose S.B. , Twyman R.M. (2003). Principle of Genome Analysis and Genomics, 3rd Edition, Hong Kong: Graphicraft Limited. Page 9
  3. Trent, R.J. (2012) Molecular Medicine Genomics to personalized healthcare: Proteomics, 4th Edition, USA :Elsevier. Chapter 4, Page 137
  4. Trent, R.J. (2012) Molecular Medicine Genomics to personalized healthcare: Proteomics, 4th Edition, USA :Elsevier. Chapter 4, Page 137
  5. Trent, R.J. (2012) Molecular Medicine Genomics to personalized healthcare: Proteomics, 4th Edition, USA :Elsevier. Chapter 4, Page 137
  6. Trent, R.J. (2012) Molecular Medicine Genomics to personalized healthcare: Proteomics, 4th Edition, USA :Elsevier. Chapter 4, Page 137
  7. Trent, R.J. (2012) Molecular Medicine Genomics to personalized healthcare: Proteomics, 4th Edition, USA :Elsevier. Chapter 4, Page 137
  8. Trent, R.J. (2012) Molecular Medicine Genomics to personalized healthcare: Proteomics, 4th Edition, USA :Elsevier. Chapter 4, Page 137
Personal tools
Namespaces
Variants
Actions
Navigation
Toolbox