Pyruvate decarboxylase

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(Created page with 'Pyruvate decarboxylase is an enzyme which removes a CO<sub>2</sub> molecule from pyruvate to give an acetaldehyde, and is notably the&nbsp…')
 
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Pyruvate decarboxylase is an enzyme which removes&nbsp;a&nbsp;CO<sub>2</sub> molecule from [[pyruvate|pyruvate]] to give an [[acetaldehyde|acetaldehyde]], and is notably the&nbsp;first enzyme in the [[Pyruvate_Dehydrogenase_Complex|pyruvate dehydrogenase complex]]. It is a heterotetramer consisting of 2 alpha and 2 beta subunits. The alpha subunits are encoded by [[PDHA1 gene|PDHA1 gene]] which is located on Xp22.2-p22.1, the beta subunits are encoded by the&nbsp;[[PDHB|PDHB ]]gene, which is located on chromosone 3p. The active site for the [[Enzyme|enzyme]] is contained on the alpha subunit.&nbsp;
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Pyruvate decarboxylase is an enzyme which removes&nbsp;a&nbsp;CO<sub>2</sub> molecule from [[Pyruvate|pyruvate]] to give an [[Acetaldehyde|acetaldehyde]], and is notably the&nbsp;first enzyme in the [[Pyruvate Dehydrogenase Complex|pyruvate dehydrogenase complex]]. It is a heterotetramer consisting of 2 alpha and 2 beta subunits<references />[http://www.ncbi.nlm.nih.gov/omim/300502 http://www.ncbi.nlm.nih.gov/omim/300502]<references />. The alpha subunits are encoded by [[PDHA1 gene|PDHA1 gene]] which is located on Xp22.2-p22.1, the beta subunits are encoded by the&nbsp;[[PDHB|PDHB gene]], which is located on chromosone 3p. The active site for the [[Enzyme|enzyme]] is contained on the alpha subunit.&nbsp; <span id="fck_dom_range_temp_1289589229843_695" />
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Revision as of 19:20, 12 November 2010

Pyruvate decarboxylase is an enzyme which removes a CO2 molecule from pyruvate to give an acetaldehyde, and is notably the first enzyme in the pyruvate dehydrogenase complex. It is a heterotetramer consisting of 2 alpha and 2 beta subunitshttp://www.ncbi.nlm.nih.gov/omim/300502. The alpha subunits are encoded by PDHA1 gene which is located on Xp22.2-p22.1, the beta subunits are encoded by the PDHB gene, which is located on chromosone 3p. The active site for the enzyme is contained on the alpha subunit.  <span id="fck_dom_range_temp_1289589229843_695" />

 

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