Quaternary structure

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The quaternary structure of a [[Protein|protein]]&nbsp;refers to the arrangement of cross-linked proteins (several [[polypeptide|polypeptide]] chains inter-linked).&nbsp;The structure is held together by [[Hydrogen bonds|hydrogen bonds]], [[Disulphide bond|disulphide bonds]], [[Ionic bond|ionic bonds]] and [[Hydrophobic interaction|hydrophobic interactions]]&nbsp;<ref>Biology 1 for OCR, Mary Jones, Cambridge University Press (2008)</ref>.
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The quaternary structure of a [[Protein|protein]]&nbsp;is the fourth level of organisation. It refers to the arrangement of cross-linked proteins (several [[Polypeptide|polypeptide]] chains inter-linked).&nbsp;The structure is held together by [[Hydrogen bonds|hydrogen bonds]], [[Disulphide bond|disulphide bonds]], [[Ionic bond|ionic bonds]] and [[Hydrophobic interaction|hydrophobic interactions]]&nbsp;<ref>Biology 1 for OCR, Mary Jones, Cambridge University Press (2008)</ref>.  
  
=== References ===
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The simplest form is when two polypeptide chains (2 subunits) form a dimer, a more complicated example is that of haemoglobin. Haemoglobin has 4 subunits which interact to form the quaternary structure. Small changes to this allow it to carry oxygen round the body to organs.
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=== References ===
  
 
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Revision as of 16:55, 15 November 2012

The quaternary structure of a protein is the fourth level of organisation. It refers to the arrangement of cross-linked proteins (several polypeptide chains inter-linked). The structure is held together by hydrogen bonds, disulphide bonds, ionic bonds and hydrophobic interactions [1].

The simplest form is when two polypeptide chains (2 subunits) form a dimer, a more complicated example is that of haemoglobin. Haemoglobin has 4 subunits which interact to form the quaternary structure. Small changes to this allow it to carry oxygen round the body to organs.

References

  1. Biology 1 for OCR, Mary Jones, Cambridge University Press (2008)

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