Ran-GAP

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Ran-GAP is a GTPase-activating protein in the cytosol involved in the conversion of Ran-GTP to Ran-GDP in nuclear import. The hydrolysis of Ran-GTP to Ran-GDP causes the release of the import receptor which makes it available to bind more cargo to import into the nuclear through the [[NPC|NPC]]. 
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Ran-GAP is a GTPase-activating protein in the cytosol involved in the conversion of Ran-GTP to Ran-GDP in nuclear import. The hydrolysis of Ran-GTP to Ran-GDP causes the release of the import receptor which makes it available to bind more cargo to import into the nuclear through the nuclear pore complex.&nbsp;<ref>Bruce Alberts, Alexander Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter. Molecular Biology of the Cell. 2008, Garland Science, New York
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Page 653</ref>
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= References:&nbsp; =
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<references />

Revision as of 19:14, 3 December 2017

 Ran-GAP

Ran-GAP is a GTPase-activating protein in the cytosol involved in the conversion of Ran-GTP to Ran-GDP in nuclear import. The hydrolysis of Ran-GTP to Ran-GDP causes the release of the import receptor which makes it available to bind more cargo to import into the nuclear through the nuclear pore complex. [1]


References: 

  1. Bruce Alberts, Alexander Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter. Molecular Biology of the Cell. 2008, Garland Science, New York Page 653
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