Recombination

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Recombination is a process that involves crossing over between chromosomes which subsequently results in exchange of genetic material between the chromosomes. There are three types of genetic recombination and they are homologous recombination, site-specific recombination and somatic recombination. The process normally involves strand invasion followed by strand breakage, which leads to formation of Holliday junction. Resolution of Holliday junction gives rise crossover or noncrossover products. Mismatch repair of heteroduplexes which usually occurs after that may lead to gene conversion.&nbsp;<br>
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Recombination is a process that involves crossing over between chromosomes which subsequently results in exchange of genetic material between the chromosomes. There are three types of genetic recombination and they are homologous recombination, site-specific recombination and somatic recombination. The process normally involves strand invasion followed by strand breakage, which leads to formation of Holliday junction. Resolution of Holliday junction gives rise crossover or noncrossover products. Mismatch repair of heteroduplexes which usually occurs after that may lead to gene conversion. There are several models for genetic recombination, and they include the Double Holliday Junction(DHJ) model and Synthesis-Dependent Strand Annealing(SDSA) model<br>  
  
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Homologous recombination, [[Principle of Independent Assortment|independent assortment]] of chromosomes during meiosis and random fertilisation of parental gametes are the main contributors of genetic variation in offspring.
  
Homologous recombination, [[Principle_of_Independent_Assortment|independent assortment]] of chromosomes during meiosis and random fertilisation of parental gametes are the main contributors of genetic variation in offspring.
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Homologous recombination during meiosis may prevent [[Gene_linkage|gene linkage]].

Revision as of 13:37, 15 November 2013

Recombination is a process that involves crossing over between chromosomes which subsequently results in exchange of genetic material between the chromosomes. There are three types of genetic recombination and they are homologous recombination, site-specific recombination and somatic recombination. The process normally involves strand invasion followed by strand breakage, which leads to formation of Holliday junction. Resolution of Holliday junction gives rise crossover or noncrossover products. Mismatch repair of heteroduplexes which usually occurs after that may lead to gene conversion. There are several models for genetic recombination, and they include the Double Holliday Junction(DHJ) model and Synthesis-Dependent Strand Annealing(SDSA) model


Homologous recombination, independent assortment of chromosomes during meiosis and random fertilisation of parental gametes are the main contributors of genetic variation in offspring.


Homologous recombination during meiosis may prevent gene linkage.

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