Retrotransposon

From The School of Biomedical Sciences Wiki
(Difference between revisions)
Jump to: navigation, search
(what are retrotransposons)
 
(Cleaned up the references. Added some links.)
Line 1: Line 1:
Retrotransposon are a class of [[Trsnaposons|transposons]]&nbsp;which operate by DNA being transcribed into RNA then back to DNA again, via the action of reverse trnascriptase<ref>Lander E, Linton L, Birren B, Nusbaum C, Zody M, Baldwin J et al. Initial sequencing and analysis of the human genome. Nature [Internet]. 2001</ref>. They are also known as 'jumping genes' as DNA is moved to a different position on the chromosome each time retrotransposition occurs<ref>Lander E, Linton L, Birren B, Nusbaum C, Zody M, Baldwin J et al. Initial sequencing and analysis of the human genome. Nature [Internet]. 2001</ref>.&nbsp;<br>
+
Retrotransposon are a class of [[Trsnaposons|transposons]] which operate by [[DNA|DNA]] being transcribed into [[RNA|RNA]] then back to DNA again, via the action of [[reverse trnascriptase|reverse trnascriptase]]<ref>Lander E, Linton L, Birren B, Nusbaum C, Zody M, Baldwin J et al. Initial sequencing and analysis of the human genome. Nature [Internet]. 2001</ref>. They are also known as 'jumping genes' as DNA is moved to a different position on the chromosome each time retrotransposition occurs<ref>Lander E, Linton L, Birren B, Nusbaum C, Zody M, Baldwin J et al. Initial sequencing and analysis of the human genome. Nature [Internet]. 2001</ref>.  
  
<br>  
+
There are 2 types of retrotransposons<ref>The three Types of Retrotransposons [Internet]. Actforlibraries.org. 2018</ref>:
  
There are 2 types of retrotransposons<ref>The three Types of Retrotransposons [Internet]. Actforlibraries.org. 2018</ref>:&nbsp;
+
#Long Terminal Receptors ([[Long terminal receptor|LTRs]]) - these have structures similar to [[Retroviruses|retroviruses]]
 +
#Non-Long Terminal Receptors ([[Non long terminal receptor|non LTRs]]) - these are further divided into Long Interspersed Nuclear Elements ([[Long interspersed nuclear elements|LINEs]]) and Short Interspersed Nuclear Elements ([[Short interspersed nuclear elements|SINEs]])
  
1. Long Terminal Receptors ([[Long terminal receptor|LTRs]])&nbsp;
+
=== References  ===
  
These have structures similar to [[Retroviruses|retroviruses]]
+
<references />
 
+
2. Non-Long Terminal Receptors ([[Non long terminal receptor|non LTRs]])&nbsp;
+
 
+
These are further divided into Long Interspersed Nuclear Elements ([[Long interspersed nuclear elements|LINEs]]) and Short Interspersed Nuclear Elements ([[Short interspersed nuclear elements|SINEs]])&nbsp;<br>
+

Revision as of 11:51, 3 December 2018

Retrotransposon are a class of transposons which operate by DNA being transcribed into RNA then back to DNA again, via the action of reverse trnascriptase[1]. They are also known as 'jumping genes' as DNA is moved to a different position on the chromosome each time retrotransposition occurs[2].

There are 2 types of retrotransposons[3]:

  1. Long Terminal Receptors (LTRs) - these have structures similar to retroviruses
  2. Non-Long Terminal Receptors (non LTRs) - these are further divided into Long Interspersed Nuclear Elements (LINEs) and Short Interspersed Nuclear Elements (SINEs)

References

  1. Lander E, Linton L, Birren B, Nusbaum C, Zody M, Baldwin J et al. Initial sequencing and analysis of the human genome. Nature [Internet]. 2001
  2. Lander E, Linton L, Birren B, Nusbaum C, Zody M, Baldwin J et al. Initial sequencing and analysis of the human genome. Nature [Internet]. 2001
  3. The three Types of Retrotransposons [Internet]. Actforlibraries.org. 2018
Personal tools
Namespaces
Variants
Actions
Navigation
Toolbox