Retrotransposon

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Retrotransposon are a class of transposons which operate by DNA being transcribed into RNA then back to DNA again, via the action of reverse trnascriptase[1]. They are also known as 'jumping genes' as DNA is moved to a different position on the chromosome each time retrotransposition occurs[2].

There are 2 types of retrotransposons[3]:

  1. Long Terminal Receptors (LTRs) - these have structures similar to retroviruses
  2. Non-Long Terminal Receptors (non LTRs) - these are further divided into Long Interspersed Nuclear Elements (LINEs) and Short Interspersed Nuclear Elements (SINEs)

References

  1. Lander E, Linton L, Birren B, Nusbaum C, Zody M, Baldwin J et al. Initial sequencing and analysis of the human genome. Nature [Internet]. 2001
  2. Lander E, Linton L, Birren B, Nusbaum C, Zody M, Baldwin J et al. Initial sequencing and analysis of the human genome. Nature [Internet]. 2001
  3. The three Types of Retrotransposons [Internet]. Actforlibraries.org. 2018
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