Rna polymerases in eukaryotes

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Three types of RNA polymerases exist in eukaryotes- RNA polymerase I, RNA polymerase II and RNA polymerase III. These polymerases have different locations in the nucleus, respond to different inhibitors and are specific to different templates. See table 1 for details of these polymerases.
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Three types of [[RNA|RNA]] polymerases exist in eukaryotes- [[RNA polymerase I|RNA polymerase I]], [[RNA polymerase II|RNA polymerase II]] and [[RNA polymerase III|RNA polymerase III]]. These polymerases have different locations in the [[Nucleus|nucleus]], respond to different inhibitors and are specific to different templates. See table 1 for details of these polymerases.  
  
 
 Table 1: RNA Polymerases in Eukaryotes     
 
 Table 1: RNA Polymerases in Eukaryotes     
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|-
 
| Type  
 
| Type  
| Location
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| Location  
| Cellular Transcripts
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| Cellular Transcripts  
 
| Effects of Alpha amanitin
 
| Effects of Alpha amanitin
 
|-
 
|-
| I
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| I  
| Nucleolus
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| [[Nucleus|Nucleolus]]
| 18S, 5.8S,and 28S rRNA
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| 18S, 5.8S,and 28S rRNA  
 
| Insensitive
 
| Insensitive
 
|-
 
|-
| II
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| II  
| Nucleus
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| [[Nucleus|Nucleus]]
| mRNA, precursors and snRNA
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| [[MRNA|mRNA]], precursors and snRNA  
 
| strongly inhibited
 
| strongly inhibited
 
|-
 
|-
| III
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| III  
| Nucleus
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| [[Nucleus|Nucleus]]
| tRNA and 5S rRNA
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| [[TRNA|tRNA]] and 5S rRNA  
 
| Inhibited by high concentrations
 
| Inhibited by high concentrations
 
|}
 
|}
  
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''Pg 834, Biochemistry 6th Edition (2006)&nbsp;<ref>Berg M. J., Tymoczko L. J., Stryer L., (2006) Biochemistry, 6th Edition New York: W. H Freeman</ref>''
  
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=== References ===
  
''Pg 834, Biochemistry 6th Edition (2006)''
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<references />
 
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<references />Berg M. J., Tymoczko L. J., Stryer L., (2006)&nbsp;Biochemistry, 6th Edition New York: W. H Freeman
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Latest revision as of 19:00, 23 November 2010

Three types of RNA polymerases exist in eukaryotes- RNA polymerase I, RNA polymerase II and RNA polymerase III. These polymerases have different locations in the nucleus, respond to different inhibitors and are specific to different templates. See table 1 for details of these polymerases.

 Table 1: RNA Polymerases in Eukaryotes   

Type Location Cellular Transcripts Effects of Alpha amanitin
I Nucleolus 18S, 5.8S,and 28S rRNA Insensitive
II Nucleus mRNA, precursors and snRNA strongly inhibited
III Nucleus tRNA and 5S rRNA Inhibited by high concentrations

Pg 834, Biochemistry 6th Edition (2006) [1]

References

  1. ↑ Berg M. J., Tymoczko L. J., Stryer L., (2006) Biochemistry, 6th Edition New York: W. H Freeman
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