Rna polymerases in eukaryotes

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|-
 
|-
 
| I  
 
| I  
| [[Nucleus|Nucleolus]]
+
| [[Nucleus|Nucleolus]]  
 
| 18S, 5.8S,and 28S rRNA  
 
| 18S, 5.8S,and 28S rRNA  
 
| Insensitive
 
| Insensitive
 
|-
 
|-
 
| II  
 
| II  
| [[Nucleus|Nucleus]]
+
| [[Nucleus|Nucleus]]  
| [[mRNA|mRNA]], precursors and snRNA  
+
| [[MRNA|mRNA]], precursors and snRNA  
 
| strongly inhibited
 
| strongly inhibited
 
|-
 
|-
 
| III  
 
| III  
| [[Nucleus|Nucleus]]
+
| [[Nucleus|Nucleus]]  
| [[tRNA|tRNA]] and 5S rRNA  
+
| [[TRNA|tRNA]] and 5S rRNA  
 
| Inhibited by high concentrations
 
| Inhibited by high concentrations
 
|}
 
|}
  
''Pg 834, Biochemistry 6th Edition (2006)&nbsp;<ref>Berg M. J., Tymoczko L. J., Stryer L., (2006) Biochemistry, 6th Edition New York: W. H Freeman</ref>''
+
''Pg 834, Biochemistry 6th Edition (2006)&nbsp;<ref>Berg M. J., Tymoczko L. J., Stryer L., (2006) Biochemistry, 6th Edition New York: W. H Freeman</ref>''  
References ===
+
 
 +
=== References ===  
  
 
<references />
 
<references />

Latest revision as of 19:00, 23 November 2010

Three types of RNA polymerases exist in eukaryotes- RNA polymerase I, RNA polymerase II and RNA polymerase III. These polymerases have different locations in the nucleus, respond to different inhibitors and are specific to different templates. See table 1 for details of these polymerases.

 Table 1: RNA Polymerases in Eukaryotes   

Type Location Cellular Transcripts Effects of Alpha amanitin
I Nucleolus 18S, 5.8S,and 28S rRNA Insensitive
II Nucleus mRNA, precursors and snRNA strongly inhibited
III Nucleus tRNA and 5S rRNA Inhibited by high concentrations

Pg 834, Biochemistry 6th Edition (2006) [1]

References

  1. Berg M. J., Tymoczko L. J., Stryer L., (2006) Biochemistry, 6th Edition New York: W. H Freeman
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