Rna polymerases in eukaryotes
From The School of Biomedical Sciences Wiki
Three types of RNA polymerases exist in eukaryotes- RNA polymerase I, RNA polymerase II and RNA polymerase III. These polymerases have different locations in the nucleus, respond to different inhibitors and are specific to different templates. See table 1 for details of these polymerases.
Table 1: RNA Polymerases in Eukaryotes
| Type | Location | Cellular Transcripts | Effects of Alpha amanitin |
| I | Nucleolus | 18S, 5.8S,and 28S rRNA | Insensitive |
| II | Nucleus | mRNA, precursors and snRNA | strongly inhibited |
| III | Nucleus | tRNA and 5S rRNA | Inhibited by high concentrations |
Pg 834, Biochemistry 6th Edition (2006)
Berg M. J., Tymoczko L. J., Stryer L., (2006) Biochemistry, 6th Edition New York: W. H Freeman
