Rna polymerases in eukaryotes

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Three types of RNA polymerases exist in eukaryotes- RNA polymerase I, RNA polymerase II and RNA polymerase III. These polymerases have different locations in the nucleus, respond to different inhibitors and are specific to different templates. See table 1 for details of these polymerases.

 Table 1: RNA Polymerases in Eukaryotes   

Type Location Cellular Transcripts Effects of Alpha amanitin
I Nucleolus 18S, 5.8S,and 28S rRNA Insensitive
II Nucleus mRNA, precursors and snRNA strongly inhibited
III Nucleus tRNA and 5S rRNA Inhibited by high concentrations

Pg 834, Biochemistry 6th Edition (2006) [1] References ===

  1. Berg M. J., Tymoczko L. J., Stryer L., (2006) Biochemistry, 6th Edition New York: W. H Freeman
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