Rna splicing

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Splicing is the process in which [[Pre-mRNA|pre-mRNA]] is modified by the removal of [[Intron|introns]] to form [[MRNA|mRNA]], comprised of joined [[Exon|exons]]. I[[Intron|ntrons]] normally exist within the protein-coding sequences within the [[Genome|genome]]. Splicing is a neccessary step in many [[Eukaryotic|eukaryotic]] cells for [[Transcription|transcription]], in order for them to form functioning proteins by the secondary process of [[Translation|translation]] of the cell's mRNA. Typically, splicing is achieved through a series of reactions, catalyzed by a spliceosome, a large complex of five small nuclear ribonucleoproteins (snRNPs), however self-splicing introns do exist for introns that form ribozymes, where the function of the spliceosome is performed by the RNA alone. Although splicing exists throughout the kingdoms of life, the extent and type difers greatly. For example, although common in many eukaryotic organisms, splicing occurs rarely in [[Prokaryotes|prokaryotes]] and lacks a spliceosomal pathway.
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Splicing is the process in which [[Pre-mRNA|pre-mRNA]] is modified by the removal of [[Intron|introns]] to form [[MRNA|mRNA]], comprised of joined [[Exon|exons]]. [[Introns|Introns]] normally exist within the [[protein-coding sequence|protein-coding sequences]] within the [[Genome|genome]]. Splicing is a neccessary step in many [[Eukaryotic|eukaryotic]] cells for [[Transcription|transcription]], in order for them to form functioning [[Proteins|proteins]] by the secondary process of [[Translation|translation]] of the cell's [[mRNA|mRNA]]. Typically, splicing is achieved through a series of reactions, catalyzed by a [[spliceosome|spliceosome]], a large complex of five small nuclear [[ribonucleoproteins |ribonucleoproteins]] (snRNPs), however self-splicing introns do exist for introns that form [[ribozymes|ribozymes]], where the function of the spliceosome is performed by the RNA alone. Although splicing exists throughout the [[kingdoms of life|kingdoms of life]], the extent and type difers greatly. For example, although common in many [[Eukaryotic|eukaryotic]] organisms, splicing occurs rarely in [[Prokaryotes|prokaryotes]] and lacks a [[spliceosomal pathway|spliceosomal pathway]].

Latest revision as of 13:27, 21 October 2012

Splicing is the process in which pre-mRNA is modified by the removal of introns to form mRNA, comprised of joined exons. Introns normally exist within the protein-coding sequences within the genome. Splicing is a neccessary step in many eukaryotic cells for transcription, in order for them to form functioning proteins by the secondary process of translation of the cell's mRNA. Typically, splicing is achieved through a series of reactions, catalyzed by a spliceosome, a large complex of five small nuclear ribonucleoproteins (snRNPs), however self-splicing introns do exist for introns that form ribozymes, where the function of the spliceosome is performed by the RNA alone. Although splicing exists throughout the kingdoms of life, the extent and type difers greatly. For example, although common in many eukaryotic organisms, splicing occurs rarely in prokaryotes and lacks a spliceosomal pathway.

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