Semi-conservative replication

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Semi-conservative replication is the mechanism by which [[DNA|DNA]] replicates in [[Cell|cells]]. The &nbsp;The parent strand splits in two and uses itself as a template to form a second [[Complementary strand|complementary strand]]. The exposed bases on the single stranded DNA complementary base pair to [[Nucleotides|nucleotides]]. A (Adenine) pairs with T (Thymine) and C (Cytosine) pairs with G (Guanine).&nbsp;<ref>Alberts et al. Molecular biology of the cell fifth edition 2007. Page 266</ref>Together the template strand and the complementary strand bond together to form a new double strand of DNA.&nbsp; One parent double strand of DNA will thus become two daughter double strands of DNA&nbsp;<ref>Hartl, D and Jones, E (2009). Genetics- Analysis of genes and genomes. 7th ed. Sudbury: Jones and Bartlett publishers, Inc. 192.</ref>.<br>  
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Semi-conservative replication is the mechanism by which [[DNA|DNA]] replicates in [[Cell|cells]]. The &nbsp;The parent strand splits in two and uses itself as a template to form a second [[Complementary strand|complementary strand]]. The exposed bases on the single stranded DNA complementary base pair to [[Nucleotides|nucleotides]]. A (Adenine) pairs with T (Thymine) and C (Cytosine) pairs with G (Guanine).&nbsp;<ref>Alberts et al. Molecular biology of the cell fifth edition 2007. Page 266</ref>Together the template strand and the complementary strand bond together to form a new double strand of DNA.&nbsp; One parent double strand of DNA will thus become two daughter double strands of DNA&nbsp;<ref>Hartl, D and Jones, E (2009). Genetics- Analysis of genes and genomes. 7th ed. Sudbury: Jones and Bartlett publishers, Inc. 192.</ref>.<br>
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The new strand of [[DNA|DNA]] is made in the 5' to 3' direction as a deoxyribonucleotide is added to the 3' OH end of the chain which is catalysed by [[DNA_polymerase|DNA polymerase]].<ref>Alberts et al. Molecular biology of the cell fifth edition, 2007. Page 268</ref>
  
 
The term "semi-conservative" refers to the fact that each of daughter double helix contains one conserved strand from the parent DNA, as well as one newly synthesised strand.&nbsp;<br>[[Image:Semi-conservative replication.gif]]  
 
The term "semi-conservative" refers to the fact that each of daughter double helix contains one conserved strand from the parent DNA, as well as one newly synthesised strand.&nbsp;<br>[[Image:Semi-conservative replication.gif]]  

Revision as of 22:35, 23 November 2014

Semi-conservative replication is the mechanism by which DNA replicates in cells. The  The parent strand splits in two and uses itself as a template to form a second complementary strand. The exposed bases on the single stranded DNA complementary base pair to nucleotides. A (Adenine) pairs with T (Thymine) and C (Cytosine) pairs with G (Guanine). [1]Together the template strand and the complementary strand bond together to form a new double strand of DNA.  One parent double strand of DNA will thus become two daughter double strands of DNA [2].

The new strand of DNA is made in the 5' to 3' direction as a deoxyribonucleotide is added to the 3' OH end of the chain which is catalysed by DNA polymerase.[3]

The term "semi-conservative" refers to the fact that each of daughter double helix contains one conserved strand from the parent DNA, as well as one newly synthesised strand. 
Semi-conservative replication.gif

References

  1. Alberts et al. Molecular biology of the cell fifth edition 2007. Page 266
  2. Hartl, D and Jones, E (2009). Genetics- Analysis of genes and genomes. 7th ed. Sudbury: Jones and Bartlett publishers, Inc. 192.
  3. Alberts et al. Molecular biology of the cell fifth edition, 2007. Page 268
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