Semi-conservative replication

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Semi-conservative replication is the mechanism by which [[DNA|DNA]] replicates in [[Cell|cells]]. The parent strand splits in two and uses itself as a template to form a second [[Complementary strand|complementary strand]]. The exposed bases on the single-stranded DNA complementary base pair to [[Nucleotides|nucleotides]]. A ([[Adenine|Adenine]]) pairs with T ([[Thymine|Thymine]]) and C ([[Cytosine|Cytosine]]) pairs with G ([[Guanine|Guanine]])&nbsp;<ref>Alberts et al. Molecular biology of the cell fifth edition 2007. Page 266</ref>. Together the template strand and the complementary strand bond together to form a new double strand of DNA. One parent double strand of DNA will thus become two daughter double strands of DNA <ref>Hartl, D and Jones, E (2009). Genetics- Analysis of genes and genomes. 7th ed. Sudbury: Jones and Bartlett Publishers, Inc. 192.</ref>.  
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Semi-conservative replication is the mechanism by which [[DNA|DNA]] replicates in [[Cell|cells]]. The parent strand splits in two and uses itself as a template to form a second [[Complementary strand|complementary strand]]. The exposed bases on the single-stranded DNA complementary base pair to [[Nucleotides|nucleotides]]. A ([[Adenine|Adenine]]) pairs with T ([[Thymine|Thymine]]) and C ([[Cytosine|Cytosine]]) pairs with G ([[Guanine|Guanine]])<ref>Alberts et al. Molecular biology of the cell fifth edition 2007. Page 266</ref>. Together the template strand and the complementary strand bond together to form a new double strand of DNA. One parent double strand of DNA will thus become two daughter double strands of DNA<ref>Hartl, D and Jones, E (2009). Genetics- Analysis of genes and genomes. 7th ed. Sudbury: Jones and Bartlett Publishers, Inc. 192.</ref>.  
  
The new strand of [[DNA|DNA]] is made in the 5' to 3' direction as a deoxyribonucleotide is added to the 3' OH end of the chain which is catalysed by [[DNA polymerase|DNA polymerase]]&nbsp;<ref>Alberts et al. Molecular biology of the cell fifth edition, 2007. Page 268</ref>.
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The new strand of [[DNA|DNA]] is made in the 5' to 3' direction as a deoxyribonucleotide is added to the 3' OH end of the chain which is catalysed by [[DNA polymerase|DNA polymerase]]<ref>Alberts et al. Molecular biology of the cell fifth edition, 2007. Page 268</ref>.  
  
The term "semi-conservative" refers to the fact that each of daughter double helix contains one conserved strand from the parent DNA, as well as one newly synthesised strand&nbsp;<ref>http://www.nature.com/scitable/topicpage/Semi-Conservative-DNA-Replication-Meselson-and-Stahl-421</ref>.[[Image:Semi-conservative replication.gif]]  
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The term "semi-conservative" refers to the fact that each of the daughter double helixes contains one conserved strand from the parent DNA, as well as one newly synthesised strand<ref>http://www.nature.com/scitable/topicpage/Semi-Conservative-DNA-Replication-Meselson-and-Stahl-421</ref>.[[Image:Semi-conservative replication.gif]]  
  
 
=== References  ===
 
=== References  ===
  
 
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Revision as of 14:22, 2 December 2018

Semi-conservative replication is the mechanism by which DNA replicates in cells. The parent strand splits in two and uses itself as a template to form a second complementary strand. The exposed bases on the single-stranded DNA complementary base pair to nucleotides. A (Adenine) pairs with T (Thymine) and C (Cytosine) pairs with G (Guanine)[1]. Together the template strand and the complementary strand bond together to form a new double strand of DNA. One parent double strand of DNA will thus become two daughter double strands of DNA[2].

The new strand of DNA is made in the 5' to 3' direction as a deoxyribonucleotide is added to the 3' OH end of the chain which is catalysed by DNA polymerase[3].

The term "semi-conservative" refers to the fact that each of the daughter double helixes contains one conserved strand from the parent DNA, as well as one newly synthesised strand[4].Semi-conservative replication.gif

References

  1. Alberts et al. Molecular biology of the cell fifth edition 2007. Page 266
  2. Hartl, D and Jones, E (2009). Genetics- Analysis of genes and genomes. 7th ed. Sudbury: Jones and Bartlett Publishers, Inc. 192.
  3. Alberts et al. Molecular biology of the cell fifth edition, 2007. Page 268
  4. http://www.nature.com/scitable/topicpage/Semi-Conservative-DNA-Replication-Meselson-and-Stahl-421
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