Silent mutation

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A silent mutation is a mutation in a [[Nucleotide|nucleotide]] sequence, which does not change the sequence of&nbsp;[[Amino acid|amino acids]]. Even regions outside the coding sequence could be affected by a silent mutation. In non-coding regions in [[DNA|DNA]], the [[Nucleotide|nucleotide sequence]] does not have [[Base|bases]] needed for the [[Protein|protein]] required<ref>Daniel L. Hartl and Elizabeth W. Jones (2009) Genetics: Genes and Genomes, 7th Edition, London, Jones and Bartlett Publishers, pg 513</ref>.  
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A silent mutation is a [[Mutation|mutation]] in a [[Nucleotide|nucleotide]] sequence, which does not change the sequence of&nbsp;[[Amino acid|amino acids]]. Even regions outside the coding sequence could be affected by a silent mutation. In non-coding regions in [[DNA|DNA]], the [[Nucleotide|nucleotide sequence]] does not have [[Base|bases]] needed for the [[Protein|protein]] required<ref>Daniel L. Hartl and Elizabeth W. Jones (2009) Genetics: Genes and Genomes, 7th Edition, London, Jones and Bartlett Publishers, pg 513</ref>.  
  
Silent mutations do not affect the phenotype as there are no change in amino acid sequence<ref>http://ghr.nlm.nih.gov/glossary=silentmutation November 24, 2014.</ref>.<br>  
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Silent mutations do not affect the phenotype as there are no change in amino acid sequence<ref>http://ghr.nlm.nih.gov/glossary=silentmutation November 24, 2014.</ref>.<br>
  
 
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Latest revision as of 16:03, 3 December 2015

A silent mutation is a mutation in a nucleotide sequence, which does not change the sequence of amino acids. Even regions outside the coding sequence could be affected by a silent mutation. In non-coding regions in DNA, the nucleotide sequence does not have bases needed for the protein required[1].

Silent mutations do not affect the phenotype as there are no change in amino acid sequence[2].

References:

  1. Daniel L. Hartl and Elizabeth W. Jones (2009) Genetics: Genes and Genomes, 7th Edition, London, Jones and Bartlett Publishers, pg 513
  2. http://ghr.nlm.nih.gov/glossary=silentmutation November 24, 2014.


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