Silent mutation
From The School of Biomedical Sciences Wiki
A silent mutation is a mutation in a nucleotide sequence, which does not change the sequence of amino acids. Even regions outside the coding sequence could be affected by a silent mutation. In non-coding regions in DNA, the nucleotide sequence does not have bases needed for the protein required[1].
Silent mutations do not affect the phenotype as there are no change in amino acid sequence[2].
References:
- ↑ Daniel L. Hartl and Elizabeth W. Jones (2009) Genetics: Genes and Genomes, 7th Edition, London, Jones and Bartlett Publishers, pg 513
- ↑ http://ghr.nlm.nih.gov/glossary=silentmutation November 24, 2014.
