Sodium-calcium Exchanger

From The School of Biomedical Sciences Wiki
Revision as of 15:41, 3 December 2015 by 150058186 (Talk | contribs)
(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to: navigation, search

The sodium-calcium exchanger is an antiporter in the plasma membrane of a cell that transports sodium ions into the cell and calcium ions out of the cell by secondary active transport. It uses the downward Na+ gradient into the cell created by sodium pumps using ATP to power the uphill transport of Ca2+ out of the cell. It is effective at high Ca2+ concentrations.

The sodium-calcium exchanger is important in the regulation of calcium ions in a cell. Cytosolic calcium concentration is kept low because calcium ions can act as a trigger for many processes, such as muscle contraction and cell signalling pathways.

Personal tools
Namespaces
Variants
Actions
Navigation
Toolbox