Start Codon

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The start codon for any polypeptide chain is not always AUG at some circumtances, which codes for Methionine. tRNAMet is bound to AUG and begins polypeptide synthesis[1].

Many polypeptides, however, have the methionine cleaved off after translation is complete, so AUG codon will not always be present in base sequences and not counted as in total number of amino acid as start and stop codon are not counted as amino acid at the end of the reaction of binding protein


  1. Daniel L. Hartl and Maryellen Ruvolo (2012) Genetics: Analysis of genes and genomes. 8th Edition. USA: Jones and Bartlett Learning, p.26
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