Succinate dehydrogenase

From The School of Biomedical Sciences Wiki
Revision as of 03:46, 20 October 2014 by 130055538 (Talk | contribs)
(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to: navigation, search

Succinate dehydrogenase, or mitochondrial respiratory Complex II or succinate:ubiquinone oxidoreductase (SQR) is an enzyme that catalyses the oxidation reaction between succinate and fumarate (FAD removes two hydrogen atoms from succinate, resulting in a double bond formation between the two carbon atoms, giving the product fumerate)[1]. It has four subunits: two hydrophilic proteins (flavoprotein and iron-sulfur protein) and two transmembrane proteins (CybL and CybS)[2].


  1. Alberts, Bruce. "2." Molecular Biology of the Cell. 5th ed. New York: Garland Science, 2008. 122-23. Print.
  2. Sun F, Huo X, Zhai Y, Wang A, Xu J, Su D et al. (2005). "Crystal structure of mitochondrial respiratory membrane protein complex II.". Cell 121 (7): 1043–57. doi:10.1016/j.cell.2005.05.025. PMID 15989954.
Personal tools