TFIIB

From The School of Biomedical Sciences Wiki
(Difference between revisions)
Jump to: navigation, search
 
Line 1: Line 1:
 TFIIB is one of the eukaryotic general transcription factors (the rest of them being TFIIA, TFIID, TFIIE, TFIIF, TFIIH). It helps [[RNA_polymerase_II]] to bind to the [[Promoter]] and promoter clearence.  TFIIB has a characteristic zinc finger (DNA binding domain) at the N-terminus. It also binds to the TBP ([[Tata_box]] binding protein) stabilising it to the [[DNA]] strand containing the TATA element. 
+
TFIIB is one of the eukaryotic [[General transcription factors|general transcription factors]] (the rest of them being [[TFIIA|TFIIA]], [[TFIID|TFIID]], [[TFIIE|TFIIE]], [[TFIIF|TFIIF]], [[TFIIH|TFIIH]]). It helps [[RNA polymerase II]] to bind to the [[Promoter|promoter]] and promoter clearence.  TFIIB has a characteristic [[zinc finger|zinc finger]] ([[DNA binding domain|DNA binding domain]]) at the [[N terminal|N-terminus]]. It also binds to the TBP ([[Tata box]] binding protein) stabilising it to the [[DNA]] strand containing the [[TATA element|TATA element]]. 

Latest revision as of 09:20, 28 November 2011

TFIIB is one of the eukaryotic general transcription factors (the rest of them being TFIIA, TFIID, TFIIE, TFIIF, TFIIH). It helps RNA polymerase II to bind to the promoter and promoter clearence.  TFIIB has a characteristic zinc finger (DNA binding domain) at the N-terminus. It also binds to the TBP (Tata box binding protein) stabilising it to the DNA strand containing the TATA element

Personal tools
Namespaces
Variants
Actions
Navigation
Toolbox