TFIIB

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(Created page with " TFIIB is one of the eukaryotic general transcription factors (the rest of them being TFIIA, TFIID, TFIIE, TFIIF, TFIIH). It helps RNA ploymerase II to bind to the promotor ...")
 
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 TFIIB is one of the eukaryotic general transcription factors (the rest of them being TFIIA, TFIID, TFIIE, TFIIF, TFIIH). It helps RNA ploymerase II to bind to the promotor and promotor clearence.  TFIIB has a characteristic zinc finger (DNA binding domain) at the N-terminus. It also binds to the TBP (TATA bindin protein) stabilising it to the DNA strand containing the TATA element. 
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 TFIIB is one of the eukaryotic general transcription factors (the rest of them being TFIIA, TFIID, TFIIE, TFIIF, TFIIH). It helps [[RNA_polymerase_II]] to bind to the [[Promoter]] and promoter clearence.  TFIIB has a characteristic zinc finger (DNA binding domain) at the N-terminus. It also binds to the TBP ([[Tata_box]] binding protein) stabilising it to the [[DNA]] strand containing the TATA element. 

Revision as of 08:23, 28 November 2011

 TFIIB is one of the eukaryotic general transcription factors (the rest of them being TFIIA, TFIID, TFIIE, TFIIF, TFIIH). It helps RNA_polymerase_II to bind to the Promoter and promoter clearence.  TFIIB has a characteristic zinc finger (DNA binding domain) at the N-terminus. It also binds to the TBP (Tata_box binding protein) stabilising it to the DNA strand containing the TATA element. 

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