Translation

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Translation in an important, and complex feature of the process of [[Protein synthesis|protein synthesis]]. Genetic information codes for [[Proteins|proteins]] via protein syntheis, this is an essential process as proteins are responsible for the vast majority of cell function and structure. Protein synthesis involves [[MRNA|mRNA]] and [[tRNA|tRNA]] along with other [[Proteins|proteins]] and has three main steps:  
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Translation in an important, and complex feature of the process of [[Protein synthesis|protein synthesis]]. Genetic information codes for [[Proteins|proteins]] via protein syntheis, this is an essential process as proteins are responsible for the vast majority of cell function and structure. Protein synthesis involves [[MRNA|mRNA]] and [[TRNA|tRNA]] along with other [[Proteins|proteins]] and has three main steps:  
  
 
#DNA replication  
 
#DNA replication  
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#Translation
 
#Translation
  
Translation is the most complex, it consists of the [[Nucleotide|nucleotide]] sequence of [[mRNA|mRNA]] being translated into the [[Amino_acid|amino acid]] secquence of the specific protein. The direction that translation is carried out is very significant; it occurs in the same direction as transcription ( 5'-3') this results in proteins being produced more efficiently as translation can occur during transcription&nbsp;<ref>Berg et al., 2007:869</ref>.
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Translation is the most complex, it consists of the [[Nucleotide|nucleotide]] sequence of [[MRNA|mRNA]] being translated into the [[Amino acid|amino acid]] secquence of the specific protein. The direction that translation is carried out is very significant; it occurs in the same direction as transcription ( 5'-3') this results in proteins being produced more efficiently as translation can occur during transcription&nbsp;<ref>Berg et al., 2007:869</ref>.  
  
 
The [[MRNA|mRNA]]&nbsp;and [[TRNA|tRNA]] play very important specific roles during translation; firstly [[MRNA|mRNA]] acts as a template for the production of the polypeptide chain from the genetic code. The genetic code had three important features:  
 
The [[MRNA|mRNA]]&nbsp;and [[TRNA|tRNA]] play very important specific roles during translation; firstly [[MRNA|mRNA]] acts as a template for the production of the polypeptide chain from the genetic code. The genetic code had three important features:  
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#Degenerate
 
#Degenerate
  
The [[tRNA|tRNA]] acts as an adaptor molecule to decode the [[MRNA|mRNA]] into the protein, it interacts with the [[MRNA|mRNA]] through its anticodon.The [[TRNA|tRNA]] is also responsible for [[proof-reading|proof-reading]] the [[Amino_acids|amino acid]] chain, this ensures that mistakes are very rare (less than 1 per 10000)  
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The genetic code is degenerate because it has 64 codons but only 20 amino acids, therefore most amino acids are coded for by more than one codon. 61 of these codons are used for amino acids and 3 are used as stop codons which will end translation. Only 1 codon is used for the amino acid Methionine and this is the start codon (AUG).
  
=== References ===
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The [[TRNA|tRNA]] acts as an adaptor molecule to decode the [[MRNA|mRNA]] into the protein, it interacts with the [[MRNA|mRNA]] through its anticodon.The [[TRNA|tRNA]] is also responsible for [[Proof-reading|proof-reading]] the [[Amino acids|amino acid]] chain, this ensures that mistakes are very rare (less than 1 per 10000). This is done by many&nbsp;[[TRNA|tRNA]] having an editing site as well as an activation site. These change or reject [[Amino_acids|amino acids]]&nbsp;if they are larger or smaller than they should be.
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=== References ===
  
 
<references />
 
<references />

Revision as of 16:56, 10 January 2011

Translation in an important, and complex feature of the process of protein synthesis. Genetic information codes for proteins via protein syntheis, this is an essential process as proteins are responsible for the vast majority of cell function and structure. Protein synthesis involves mRNA and tRNA along with other proteins and has three main steps:

  1. DNA replication
  2. Transcription
  3. Translation

Translation is the most complex, it consists of the nucleotide sequence of mRNA being translated into the amino acid secquence of the specific protein. The direction that translation is carried out is very significant; it occurs in the same direction as transcription ( 5'-3') this results in proteins being produced more efficiently as translation can occur during transcription [1].

The mRNA and tRNA play very important specific roles during translation; firstly mRNA acts as a template for the production of the polypeptide chain from the genetic code. The genetic code had three important features:

  1. Triplet code
  2. Non-overlapping
  3. Degenerate

The genetic code is degenerate because it has 64 codons but only 20 amino acids, therefore most amino acids are coded for by more than one codon. 61 of these codons are used for amino acids and 3 are used as stop codons which will end translation. Only 1 codon is used for the amino acid Methionine and this is the start codon (AUG).

The tRNA acts as an adaptor molecule to decode the mRNA into the protein, it interacts with the mRNA through its anticodon.The tRNA is also responsible for proof-reading the amino acid chain, this ensures that mistakes are very rare (less than 1 per 10000). This is done by many tRNA having an editing site as well as an activation site. These change or reject amino acids if they are larger or smaller than they should be.

References

  1. Berg et al., 2007:869
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