Transposon

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(Added more information about transposons eg. classes, removed repeat reference.)
(Removed some stray code. Cleaned up the references.)
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<span class="GRcorrect" id="GRmark_f105da604f7f1c37380bc764b34f000df6688f00_Transposons:0">Transposons</span> are [[Gene|genes]] that can move<span class="GRcorrect" id="GRmark_f105da604f7f1c37380bc764b34f000df6688f00_.:1">.&nbsp;</span>They have a specific target site<span class="GRcorrect" id="GRmark_f105da604f7f1c37380bc764b34f000df6688f00_.2C:2">,</span>allowing them to move or 'jump' into different [[DNA|DNA]] sites<ref>Bruce Alberts,Alexander Johnson,Julian Lewis,Martin Raff,Keith Roberts and Peter Walter (2002) Molecular Biology Of The Cell,4th edition,New York: Garland Science.p287</ref>.&nbsp;Transposons leave copies of themselves wherever they stop.&nbsp;Half of the&nbsp;<span style="font-size: 13.28px;">[[Human genome|human genom]]</span><span style="font-size: 13.28px;">[[Human genome|e]] consists of these 'jumping genes'&nbsp;</span><ref>Hardin, J. Bertoni, G. Kleinsmith, L (2012). Becker's World of the Cell. 8th ed. San Francisco: Pearson: 527</ref><span style="font-size: 13.28px;">. They are important for genomic variation and </span>[[Evolution|evolution]]<span style="font-size: 13.28px;"> in organisms. Transposons are subdivided into 2 classes:</span>
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Transposons are [[Gene|genes]] that can move. They have a specific target site,allowing them to move or 'jump' into different [[DNA|DNA]] sites<ref>Bruce Alberts,Alexander Johnson,Julian Lewis,Martin Raff,Keith Roberts and Peter Walter (2002) Molecular Biology Of The Cell,4th edition,New York: Garland Science.p287</ref>. Transposons leave copies of themselves wherever they stop. Half of the [[Human genome|human genom]][[Human genome|e]] consists of these 'jumping genes'<ref>Hardin, J. Bertoni, G. Kleinsmith, L (2012). Becker's World of the Cell. 8th ed. San Francisco: Pearson: 527</ref>. They are important for genomic variation and [[Evolution|evolution]] in organisms. Transposons are subdivided into 2 classes:  
  
*'''Class I transposons''' - also called retrotransposons - they make up 40% of the human genome. They move from one genome to another via a 'copy and paste' mechanism in which an RNA intermediate is transcribed from the retrotransposon, then made into cDNA via [[Reverse transcriptase|reverse transcriptase]] where it binds to the recipient DNA. The original genomic region containing the retrotransposon is not deleted.  
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*'''Class I transposons''' - also called [[retrotransposons|retrotransposons]] - they make up 40% of the human genome. They move from one genome to another via a 'copy and paste' mechanism in which an RNA intermediate is transcribed from the retrotransposon, then made into cDNA via [[Reverse transcriptase|reverse transcriptase]] where it binds to the recipient DNA. The original genomic region containing the retrotransposon is not deleted.  
 
*'''Class II transposons - '''move from one genome to another via a 'cut and paste' mechanism<ref>Kimball’s Biology Pages. Transposons: Mobile DNA. 2018 [cited 15/11/18]; Available From: http://www.biology-pages.info/T/Transposons.html</ref>.
 
*'''Class II transposons - '''move from one genome to another via a 'cut and paste' mechanism<ref>Kimball’s Biology Pages. Transposons: Mobile DNA. 2018 [cited 15/11/18]; Available From: http://www.biology-pages.info/T/Transposons.html</ref>.
  
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=== References  ===
  
 
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Revision as of 17:34, 6 December 2018

Transposons are genes that can move. They have a specific target site,allowing them to move or 'jump' into different DNA sites[1]. Transposons leave copies of themselves wherever they stop. Half of the human genome consists of these 'jumping genes'[2]. They are important for genomic variation and evolution in organisms. Transposons are subdivided into 2 classes:

References

  1. Bruce Alberts,Alexander Johnson,Julian Lewis,Martin Raff,Keith Roberts and Peter Walter (2002) Molecular Biology Of The Cell,4th edition,New York: Garland Science.p287
  2. Hardin, J. Bertoni, G. Kleinsmith, L (2012). Becker's World of the Cell. 8th ed. San Francisco: Pearson: 527
  3. Kimball’s Biology Pages. Transposons: Mobile DNA. 2018 [cited 15/11/18]; Available From: http://www.biology-pages.info/T/Transposons.html
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