Trisomy 21

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Trisomy 21 is the name given to the non-disjunction of homologous pairs of chromosomes 21 which leads to [[Down's syndrome|Down syndrome]]. "[[Trisomy|Trisomy]]" because, due to a nondisjunction event (failed separation of the [[Chromosome|chromosome]] pairs to separate during stage 1 or 2 of meiosis), there is an extra copy of [[Chromosome 21|chromosome 21]] in one of the gametes. At fertilisation, this gamete will cause the zygote to contain 3 copies of the chromosome 21.     
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Trisomy 21 is the name given to the [[Non_disjunction|non-disjunction ]] of [[Homologous_chromosomes|homologous pairs of chromosomes ]]21 which leads to [[Down's syndrome|Down syndrome]]. "[[Trisomy|Trisomy]]" because, due to a nondisjunction event (failed separation of the [[Chromosome|chromosome]] pairs to separate during stage 1 or 2 of meiosis), there is an extra copy of [[Chromosome 21|chromosome 21]] in one of the gametes. At fertilisation, this [[Gamete|gamete]] will cause the [[Zygote|zygote]] to contain 3 copies of the chromosome 21.       
  
 
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Revision as of 20:08, 28 November 2017

Trisomy 21 is the name given to the non-disjunction  of homologous pairs of chromosomes 21 which leads to Down syndrome. "Trisomy" because, due to a nondisjunction event (failed separation of the chromosome pairs to separate during stage 1 or 2 of meiosis), there is an extra copy of chromosome 21 in one of the gametes. At fertilisation, this gamete will cause the zygote to contain 3 copies of the chromosome 21.     


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