Uniport carrier

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A uniport carrier is a membrane transport protein that moves only one kind of [[Molecule|molecule]]. It does not generally require energy as it follows the concentration gradient of the molecule in question. 
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A uniport carrier is a [[Membrane transport protein|membrane transport protein]] that moves only one kind of [[Molecule|molecule]]. It does not generally require energy as it follows the concentration gradient of the molecule in question.  
  
 
=== Examples  ===
 
=== Examples  ===
  
An example of a uniporter is the [[Glucose transporter|glucose transporter]]&nbsp;(GLUT) in found in [[Erythrocyte|erythrocytes]] (reffered to as [[GLUT1|GLUT1]] to separate from other mamalian glucose transporters). This allows glucose to enter the cell via [[Facilitated diffusion|facilitated diffusion]] and it does so at approximately 50,000times the rate that it would via [[Simple diffusion|simple diffusion]]<ref>Becker's World of the Cell, Eighth Edition (J. Hardin, G.Bertoni, L.J. Kleinsmith) 2012 San Francisco:Pearson Page 203</ref><span style="line-height: 1.5em;">. This process is not active (meaning it does not require an energy input). Once inside the cell the glucose is quickly </span>[[Phosphorylation|phosphorylated]]<span style="line-height: 1.5em;"> to glucose-6-phosphate by the </span>[[Enzyme|enzyme]]<span style="line-height: 1.5em;">, hexokinase, to prevent it from diffusing out. This is also the first step in </span>[[Glycolysis|glycolysis]]<span style="line-height: 1.5em;">.<ref>Becker's World of the Cell, Eighth Edition (J. Hardin, G.Bertoni, L.J. Kleinsmith) 2012 San Francisco:Pearson Page 204</ref>&nbsp;</span><br>
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An example of a uniporter is the [[Glucose transporter|glucose transporter]] (GLUT) in found in [[Erythrocyte|erythrocytes]] (referred to as [[GLUT1|GLUT1]] to separate from other mammalian glucose transporters). This allows glucose to enter the cell via [[Facilitated diffusion|facilitated diffusion]] and it does so at approximately 50,000 times the rate that it would via [[Simple diffusion|simple diffusion]]<ref>Becker's World of the Cell, Eighth Edition (J. Hardin, G.Bertoni, L.J. Kleinsmith) 2012 San Francisco: Pearson Page 203</ref>. This process is not active (meaning it does not require an energy input). Once inside the cell the [[Glucose|glucose]] is quickly [[Phosphorylation|phosphorylated]] to [[Glucose-6-phosphate|glucose-6-phosphate]] by the [[Enzyme|enzyme]], [[Hexokinase|hexokinase]], to prevent it from diffusing out. This is also the first step in [[Glycolysis|glycolysis]]<ref>Becker's World of the Cell, Eighth Edition (J. Hardin, G.Bertoni, L.J. Kleinsmith) 2012 San Francisco: Pearson Page 204</ref>.
  
 
=== See Also  ===
 
=== See Also  ===
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[[Symporter|Symporter]]  
 
[[Symporter|Symporter]]  
  
[[Antiporter|Antiporter]]<br>
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[[Antiporter|Antiporter]]  
  
 
=== References  ===
 
=== References  ===
  
<references />
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<references />
 
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Latest revision as of 10:14, 19 November 2017

A uniport carrier is a membrane transport protein that moves only one kind of molecule. It does not generally require energy as it follows the concentration gradient of the molecule in question.

Examples

An example of a uniporter is the glucose transporter (GLUT) in found in erythrocytes (referred to as GLUT1 to separate from other mammalian glucose transporters). This allows glucose to enter the cell via facilitated diffusion and it does so at approximately 50,000 times the rate that it would via simple diffusion[1]. This process is not active (meaning it does not require an energy input). Once inside the cell the glucose is quickly phosphorylated to glucose-6-phosphate by the enzyme, hexokinase, to prevent it from diffusing out. This is also the first step in glycolysis[2].

See Also

Symporter

Antiporter

References

  1. Becker's World of the Cell, Eighth Edition (J. Hardin, G.Bertoni, L.J. Kleinsmith) 2012 San Francisco: Pearson Page 203
  2. Becker's World of the Cell, Eighth Edition (J. Hardin, G.Bertoni, L.J. Kleinsmith) 2012 San Francisco: Pearson Page 204
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