Uracil

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Uracil (U) is a [[Pyrimidine|pyrimidine]] base.&nbsp;It is&nbsp;one of the four bases found in [[RNA|RNA]]&nbsp;where it replaces [[Thymine|Thymine]] (T) which&nbsp;is found in [[DNA|DNA]].&nbsp;The structure of uracil differs from&nbsp;thymine in that thymine contains an extra methyl group on the 5-C&nbsp;carbon atom whereas uracil just has a hydrogen&nbsp;atom. However, the base-pairing&nbsp;is unaffected by the lack of this methyl group, therefore the U-A base pairs are very similar to T-A base pairs. E.g. there are 2 hydrogen&nbsp;bonds formed between the bases.<ref>Alberts, B et al. (2008). Molecular Biology of the Cell. 5th ed. US: Garland Science. page 303</ref>&nbsp;<ref>Berg, J.M. Tymoczko, J.L. Stryer, L. (2007). Biochemistry. 6th ed. New York: W.H. Freeman and Company. p109.</ref>.[[Image:0192801015 uracil 1.jpg|thumb|0192801015 uracil 1.jpg]]
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Uracil (U) is a [[Pyrimidine|pyrimidine]] base. It is one of the four bases found in [[RNA|RNA]] where it replaces [[Thymine|Thymine]] (T) which is found in [[DNA|DNA]]. The structure of uracil differs from thymine in that thymine contains an extra [[Methyl group|methyl group]] on the 5-C [[Carbon|carbon]] at[[Carbon]]om whereas [[DsRNA|uracil just]] has a [[Hydrogen|hydrogen]] atom. It has a chemical formula of C<sub>4</sub>H<sub>4</sub>N<sub>2</sub>O<sub>2</sub>. However, the base-pairing is unaffected by the lack of this [[Methyl group|methyl group]], therefore the U-A base pairs are very similar to T-A base pairs<ref>Alberts, B et al. (2008). Molecular Biology of the Cell. 5th ed. US: Garland Science. page 303</ref>&nbsp;e.g. there are 2 [[Hydrogen bonds|hydrogen bonds]] formed between the bases<ref>Berg, J.M. Tymoczko, J.L. Stryer, L. (2007). Biochemistry. 6th ed. New York: W.H. Freeman and Company. p109.</ref>.  
  
 
=== References  ===
 
=== References  ===
  
 
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Latest revision as of 09:14, 10 December 2018

0192801015 uracil 1.jpg

Uracil (U) is a pyrimidine base. It is one of the four bases found in RNA where it replaces Thymine (T) which is found in DNA. The structure of uracil differs from thymine in that thymine contains an extra methyl group on the 5-C carbon atCarbonom whereas uracil just has a hydrogen atom. It has a chemical formula of C4H4N2O2. However, the base-pairing is unaffected by the lack of this methyl group, therefore the U-A base pairs are very similar to T-A base pairs[1] e.g. there are 2 hydrogen bonds formed between the bases[2].

References

  1. Alberts, B et al. (2008). Molecular Biology of the Cell. 5th ed. US: Garland Science. page 303
  2. Berg, J.M. Tymoczko, J.L. Stryer, L. (2007). Biochemistry. 6th ed. New York: W.H. Freeman and Company. p109.
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