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0192801015 uracil 1.jpg

Uracil (U) is a pyrimidine base. It is one of the four bases found in RNA where it replaces Thymine (T) which is found in DNA. The structure of uracil differs from thymine in that thymine contains an extra methyl group on the 5-C carbon atCarbonom whereas uracil just has a hydrogen atom. It has a chemical formula of C4H4N2O2. However, the base-pairing is unaffected by the lack of this methyl group, therefore the U-A base pairs are very similar to T-A base pairs [1] e.g. there are 2 hydrogen bonds formed between the bases [2].


  1. Alberts, B et al. (2008). Molecular Biology of the Cell. 5th ed. US: Garland Science. page 303
  2. Berg, J.M. Tymoczko, J.L. Stryer, L. (2007). Biochemistry. 6th ed. New York: W.H. Freeman and Company. p109.
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