Vasoconstriction

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Vasoconstriction is the decreasing of the diameter of the lumen of blood vessels through the constriction of vascular smooth muscle[1].

It is a mechanism that can be used to help control blood pressure. Vasoconstriction of arterioles reduces their diameter. This reduction in lumen diameter causes the resistance to blood flow to increase as more of the Red Blood Cells come into contact with the arteriole walls. This causes blood pressure to increase[2].

Vasoconstriction can be triggered by myogenic autoregulation or chemical mediators such as noradrenaline, serotonin, endothelin, vasopressin and angiotensin II[3].

References

  1. Dee Unglaub Silverthorn (2010) Human Physiology An Integrated Approach, Sixth Edition, Glenview: Pearson. Page 469
  2. Dee Unglaub Silverthorn (2010) Human Physiology An Integrated Approach, Sixth Edition, Glenview: Pearson. Page 519
  3. Dee Unglaub Silverthorn (2010) Human Physiology An Integrated Approach, Sixth Edition, Glenview: Pearson. Page 520
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