LECTURE ONE

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Overview

© Jem Stach - Material intended solely for students enrolled @ Newcastle University - MSc Industrial and Commercial Biotechnology. jem.stach@newcastle.ac.uk

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Directed reading

An overview of the module; introduces the problem of antibacterial resistance and the methods being employed to overcome this most serious of problems

Walsh C, Where will new antibiotics come from? Nat Rev Microbiol. 2003 (1):65-70.

Stokes NR, Sievers J, Barker S, Bennett JM et al. Novel inhibitors of bacterial cytokinesis identified by a cell-based antibiotic screening assay. J Biol Chem. 2005 Dec 2;280(48):39709-15. Epub 2005 Sep 20

Mwangi MM, Wu SW, Zhou Y, Sieradzki K et al.Tracking the in vivo evolution of multidrug resistance in Staphylococcus aureus by whole-genome sequencing. Proc Natl Acad Sci U S A. 2007 May 29;104(22):9451-6. Epub 2007 May 21.

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*Assessment in text is correct (40% MCQ tests, 60% Report) - in audio is incorrect.