Informatics Practical - PubMed Related Information Menu - OMIM
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You should now be back looking at the paper abstract page. If not, click the browser 'Back Button' once, or click this link.
We will now look for, and examine, the OMIM (Online Mendelian Inheritance in Man) entry (or entries) for the protein.
Finding the OMIM entry
When usingh OMIM you may get a window popping up asking for a donation. You can ignore this window, unless you would like to donate.
  1. In the Related Information list click on the 'OMIM (cited)' link.
  2. On the OMIM page that opens you should see two entries - '604475' and '125265' - normally you would look at both, but for this exercise, we will examine '604475'.
  3. Click on the '604475' link.
OMIM Entry for 604475 RETICULON 4; RTN4 - search run Tuesday October 10, 2017 at 7:54:42 pm
Just as with the protein and nucleotide sequences it is possible to learn a lot about a protein or gene from the OMIM entry.
In fact, the OMIM entry acts as a review of the latest findings and information about a sequence.
Using the OMIM entry see if you can answer the following questions.
1) The protein RTN4 is also called:
One answer only.
   RTN2
   RTN3
   HEREANDTHERE
   NOWAY
   NOGO
   NODATA
   RTN5
2) What is the cytogenetic location?
One answer only.
   PKA
   2p16.1
   PKB
   IRS1
   IRAP
   Gi2
   Fred
3) Increased expression of the protein has been found in patients with:
One answer only.
   Alzhenier's Disease
   Parkinsons' Disease
   Amyotrophic lateral sclerosis
   Type I diabetes
   Type II diabetes
   Type III diabetes