View source for Ran-GAP

Ran-GAP is a [[GTPase-activating protein|GTPase-activating protein]] in the cytosol involved in the conversion of [[Ran-GTP|Ran-GTP]] to Ran-GDP in nuclear import. The [[hydrolysis|hydrolysis]] of Ran-GTP to Ran-GDP causes the release of the import receptor which makes it available to bind more cargo to import into the nucleus through the [[nuclear pore|nuclear pore]] complex<ref>Bruce Alberts, Alexander Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter. Molecular Biology of the Cell. 2008, Garland Science, New York Page 653</ref>. 

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