Poly-A tail: Difference between revisions
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The Poly-A tail is a polyadenylate sequence which is added to the 3' terminus of a eukaryotic [[mRNA|mRNA]] during RNA processing. A Poly-A tail can consist up to 200 nucleotides of [[adenosine monophosphate|adenosine monophosphate]], which greatly increases the stability of the mRNA. Before the addition of the Poly-A tail, the 3' terminus of a eukaryotic mRNA has been modified by exonuclease digestion.This allows the mRNA sequence to act as a substrate for the extension of Poly-A tail<ref>Hartl D., Ruvolo M. (2012) Genetics: Analysis of Genes and Genomes, 8th edition, Burlington, MA : Jones&amp;amp;Bartlett Learning (Page 358)</ref>. | |||
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Revision as of 03:32, 28 November 2013
The Poly-A tail is a polyadenylate sequence which is added to the 3' terminus of a eukaryotic mRNA during RNA processing. A Poly-A tail can consist up to 200 nucleotides of adenosine monophosphate, which greatly increases the stability of the mRNA. Before the addition of the Poly-A tail, the 3' terminus of a eukaryotic mRNA has been modified by exonuclease digestion.This allows the mRNA sequence to act as a substrate for the extension of Poly-A tail[1].
References
- ↑ Hartl D., Ruvolo M. (2012) Genetics: Analysis of Genes and Genomes, 8th edition, Burlington, MA : Jones&amp;Bartlett Learning (Page 358)