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A transmembrane protein&nbsp;is a [[Protein|protein]] which is associated with&nbsp;the [[Lipid_bilayer|lipid bilayer]] in the&nbsp;[[Cell membranes|membrane]]. The protein runs right through the membrane with both [[Cytosol|cytosolic]] and extracellular domains. Transmembrane proteins are [[Amphipathic|amphipathic]]; the [[Hydrophobic|hydrophobic]] regions interact with lipid tails inside the lipid bilayer and the [[hydrophillic|hydrophillic]] regions are exposed <ref>Alberts,B., Johnson,A., Lewis,J., Raff,M., Roberts,K. and Walter,P. (2008) Molecular Biology of the Cell, 5th Edition, 630</ref>.  
A transmembrane protein&nbsp;is a [[Protein|protein]] which is associated with&nbsp;the [[Lipid bilayer|lipid bilayer]] in the&nbsp;[[Cell membranes|membrane]]. The protein runs right through the membrane with both [[Cytosol|cytosolic]] and extracellular domains. Proteins can have several transmembrane domians if its polypeptide chain repeatedly crosses the lipid bilayer in the membrane. Transmembrane proteins are [[Amphipathic|amphipathic]]; the [[Hydrophobic|hydrophobic]] regions interact with lipid tails inside the lipid bilayer and the [[Hydrophillic|hydrophillic]] regions are exposed <ref>Alberts,B., Johnson,A., Lewis,J., Raff,M., Roberts,K. and Walter,P. (2008) Molecular Biology of the Cell, 5th Edition, 630</ref>.  


=== References<br> ===
=== References<br> ===


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<references />

Revision as of 14:30, 19 October 2014

A transmembrane protein is a protein which is associated with the lipid bilayer in the membrane. The protein runs right through the membrane with both cytosolic and extracellular domains. Proteins can have several transmembrane domians if its polypeptide chain repeatedly crosses the lipid bilayer in the membrane. Transmembrane proteins are amphipathic; the hydrophobic regions interact with lipid tails inside the lipid bilayer and the hydrophillic regions are exposed [1].

References

  1. Alberts,B., Johnson,A., Lewis,J., Raff,M., Roberts,K. and Walter,P. (2008) Molecular Biology of the Cell, 5th Edition, 630