Ligation: Difference between revisions
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Ligation, in molecular biology, is the process where either 2 [[DNA|DNA]] or [[RNA|RNA]] strands are joined together by an [[Enzyme|enzyme]] called [[Ligase|ligase]]. Ligation occurs during the cloning of DNA or during processes such as transformation of a [[Plasmid|plasmid]]. Ligation is important in biotechnology as it can allow for the detection and determination of changes in RNA sequences. | Ligation, in molecular biology, is the process where either 2 [[DNA|DNA]] or [[RNA|RNA]] strands are joined together by an [[Enzyme|enzyme]] called [[Ligase|ligase]]. Ligation occurs during the cloning of DNA or during processes such as transformation of a [[Plasmid|plasmid]]. Ligation is important in biotechnology as it can allow for the detection and determination of changes in RNA sequences.<ref>Nilsson et al (2001) "RNA-templated DNA ligation for transcript analysis" Nucleic acid research.</ref> | ||
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Revision as of 11:38, 23 October 2014
Ligation, in molecular biology, is the process where either 2 DNA or RNA strands are joined together by an enzyme called ligase. Ligation occurs during the cloning of DNA or during processes such as transformation of a plasmid. Ligation is important in biotechnology as it can allow for the detection and determination of changes in RNA sequences.[1]
- ↑ Nilsson et al (2001) "RNA-templated DNA ligation for transcript analysis" Nucleic acid research.