Phosphatidylethanolamine: Difference between revisions
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Phosphatidylethanolamine is one of the four main [[Phospholipids|phospholipids]] found within the lipid bilayer of mammalian [[Plasma membrane|plasma membranes]]. Three of these integral four are derived from [[Glycerol|glycerol]] however, the fourth, sphingomyelin is derived from the amino acid serine. These phospholipids within the membrane are described as being amphipathic – they have a hydrophilic (water-loving) head and a hydrophobic (water-hating) tail. | Phosphatidylethanolamine is one of the four main [[Phospholipids|phospholipids]] found within the lipid bilayer of mammalian [[Plasma membrane|plasma membranes]]. Three of these integral four are derived from [[Glycerol|glycerol]] however, the fourth, sphingomyelin is derived from the amino acid serine. These phospholipids within the membrane are described as being amphipathic – they have a hydrophilic (water-loving) head and a hydrophobic (water-hating) tail. | ||
The phosphoglyceride (glycerol derivative) structure consists of a three carbon glycerol backbone and two fatty acid tails [[Ester bond|esterified]] to neighbouring glycerol carbon atoms. The inconsistency of the polar phosphate head allows for the construction of a variety of phosphoglycerides for plasma membrane assembly, however, the three main phosphoglycerides are phophatidylserine, phosphatidylcholine, phosphatidylethanolamine.<ref>Alberts et. Al. (2008), Molecular Biology of the Cell, 5th Edition, (618-619) New York, Garland Science, Taylor and Francis Group</ref> The hydrobicity of the [[Hydrocarbons|fatty acid chain]] tails creates the bilayer effect as they avoid the water by packaging themselves with the hydrophobic heads on both the basolateral and apical membranes. These tails often include C=C double bonds which ‘kink’ the tail and allow for fluidity within the plasma membrane. | The phosphoglyceride (glycerol derivative) structure consists of a three carbon glycerol backbone and two fatty acid tails [[Ester bond|esterified]] to neighbouring glycerol carbon atoms. The inconsistency of the polar phosphate head allows for the construction of a variety of phosphoglycerides for plasma membrane assembly, however, the three main phosphoglycerides are phophatidylserine, phosphatidylcholine, phosphatidylethanolamine.<ref>Alberts et. Al. (2008), Molecular Biology of the Cell, 5th Edition, (618-619) New York, Garland Science, Taylor and Francis Group</ref> The hydrobicity of the [[Hydrocarbons|fatty acid chain]] tails creates the bilayer effect as they avoid the water by packaging themselves with the hydrophobic heads on both the basolateral and apical membranes. These tails often include C=C double bonds which ‘kink’ the tail and allow for fluidity within the plasma membrane <ref>Alberts et. Al. (2008), Molecular Biology of the Cell, 5th Edition, (618-619) New York, Garland Science, Taylor and Francis Group</ref>. | ||
=== References === | |||
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Latest revision as of 02:28, 24 October 2014
Phosphatidylethanolamine is one of the four main phospholipids found within the lipid bilayer of mammalian plasma membranes. Three of these integral four are derived from glycerol however, the fourth, sphingomyelin is derived from the amino acid serine. These phospholipids within the membrane are described as being amphipathic – they have a hydrophilic (water-loving) head and a hydrophobic (water-hating) tail.
The phosphoglyceride (glycerol derivative) structure consists of a three carbon glycerol backbone and two fatty acid tails esterified to neighbouring glycerol carbon atoms. The inconsistency of the polar phosphate head allows for the construction of a variety of phosphoglycerides for plasma membrane assembly, however, the three main phosphoglycerides are phophatidylserine, phosphatidylcholine, phosphatidylethanolamine.[1] The hydrobicity of the fatty acid chain tails creates the bilayer effect as they avoid the water by packaging themselves with the hydrophobic heads on both the basolateral and apical membranes. These tails often include C=C double bonds which ‘kink’ the tail and allow for fluidity within the plasma membrane [2].